N,N-Bis(PEG2-azide)-N-4-oxo-butanoic NHS ester
This product is a multifunctional PEG linker with dual azide groups for click chemistry and an NHS ester for amine conjugation. The PEG2 spacers enhance solubility and flexibility, making it especially effective for orthogonal bioconjugation, probe design, and multifunctional assembly.
Key Features and Benefits:
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Dual Azides: Support CuAAC or SPAAC click chemistry with alkynes.
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NHS Ester: Couples efficiently with primary amines under mild conditions.
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PEG2 Spacers: Provide hydrophilicity, solubility, and steric accessibility.
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Multifunctional Design: Enables orthogonal and stepwise conjugation.
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High Purity: Ensures reproducibility in advanced research workflows.
Applications:
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Bioconjugation: Combines amine reactivity with click-ready handles.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Facilitates dual-functional linker design for targeted release.
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Synthetic Chemistry: Serves as a versatile intermediate for scaffold construction.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid hydrolysis of the NHS ester.
This product integrates dual azide groups with amine-reactive NHS chemistry, providing versatile reactivity specifically for multifunctional conjugation, probe design, and drug delivery.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
