N,N-Bis(PEG2-azide)-N-4-oxo-butanoic acid
This product is a multifunctional PEG-based linker with two terminal azides and a carboxylic acid attached to a 4-oxo-butanoic scaffold. The dual azides enable orthogonal click chemistry, while the acid provides versatile amide coupling, making this reagent especially useful in bioconjugation, drug delivery, and advanced material applications.
Key Features and Benefits:
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Dual Azide Groups: Enable CuAAC and SPAAC click chemistry with alkynes.
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Carboxylic Acid Group: Couples efficiently with amines for stable amide formation.
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PEG2 Spacers: Provide hydrophilicity, flexibility, and reduced steric hindrance.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
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Multifunctionality: Combines click-ready azides with amine-reactive carboxyl functionality.
Applications:
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Bioconjugation: Enables multifunctional attachment of proteins, peptides, and biomolecules.
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Click Chemistry: Supports dual labeling via azide–alkyne ligation.
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Drug Delivery: PEGylated linker enhances solubility, stability, and circulation time.
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Surface Functionalization: Functionalizes nanoparticles, polymers, and hydrogels.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain azide and acid stability.
This product provides dual azide reactivity with a carboxyl handle in a compact PEG framework, making it an especially versatile tool for orthogonal conjugation and multifunctional biomaterial engineering.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
