N,N-Bis(PEG1-azide)-N-amido-PEG2-oxyamine
This product is a multifunctional PEG linker featuring dual azides for click chemistry and an oxyamine group for oxime ligation. The PEG spacers improve solubility and flexibility, making it especially useful for orthogonal bioconjugation, probe design, and multifunctional assembly.
Key Features and Benefits:
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Dual Azides: Enable CuAAC or SPAAC click chemistry with alkynes.
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Oxyamine Group: Reacts selectively with aldehydes and ketones for stable oxime linkages.
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PEG Spacers: Provide hydrophilicity, solubility, and steric accessibility.
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Orthogonal Reactivity: Supports multifunctional conjugation in stepwise workflows.
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High Purity: Ensures reproducibility in bioconjugation and probe development.
Applications:
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Bioconjugation: Couples biomolecules using orthogonal click and oxime chemistry.
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Drug Delivery: Facilitates multifunctional linkers for targeted release.
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Probe Development: Builds dual-functional imaging or diagnostic probes.
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Synthetic Chemistry: Serves as a versatile intermediate for advanced scaffold assembly.
Storage and Handling:
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Storage: Store at –20 °C in a tightly sealed, light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); protect from reducing agents to preserve azide groups.
This product integrates dual azides with an oxyamine handle, providing especially versatile orthogonal reactivity for bioconjugation, drug delivery, and advanced probe design.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
