N,N-Bis(PEG1-azide)-N-amido-PEG1-amine
N,N-Bis(PEG1-azide)-N-amido-PEG1-amine is a high-purity PEG linker with two azides for click chemistry and a primary amine for orthogonal conjugation. The short PEG1 spacers enhance solubility and flexibility while minimizing steric hindrance, enabling efficient multifunctional bioconjugation in aqueous and organic systems for drug delivery, diagnostics, and advanced materials.
Key Features and Benefits
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Dual Azide Groups: Allow simultaneous or sequential click chemistry with alkyne-functionalized molecules.
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Primary Amine: Couples efficiently to carboxylic acids or activated esters.
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PEG1 Spacers: Improve solubility and reduce steric interference.
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Multifunctional Design: Supports branched or multi-label constructs.
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High Purity: Supplied at >95% purity for reproducible, high-yield performance.
Applications
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Multifunctional Bioconjugation: Build branched or multi-labeled biomolecules.
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Protein and Peptide Modification: Attach alkyne-containing molecules while coupling to an acid or ester.
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Nanoparticle Functionalization: Introduce multiple reactive handles for targeted delivery.
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Drug Delivery Systems: Design multi-point linkers for precise payload release.
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Diagnostic Probe Development: Create multifunctional probes for imaging and sensing.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid moisture to preserve azide reactivity.
This product provides two azide click handles and an amine coupling site in a compact PEG1 framework, making it ideal for multifunctional bioconjugates, targeted delivery, and diagnostics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
