N,N-Bis(PEG1-azide)-N-4-oxo-butanoic NHS ester
This product is a multifunctional linker featuring dual PEG1-azide groups for click chemistry and an NHS ester for efficient amine conjugation. Its compact design provides hydrophilicity and orthogonal reactivity, making it especially effective for probe development, drug delivery, and multifunctional bioconjugation.
Key Features and Benefits:
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Dual Azide Groups: Enable CuAAC or SPAAC click chemistry with alkynes.
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NHS Ester: Couples rapidly with primary amines to form stable amide bonds.
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PEG1 Units: Enhance solubility and reduce steric hindrance.
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Multifunctional Design: Supports orthogonal, stepwise conjugation strategies.
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High Purity: Ensures reliable, reproducible results.
Applications:
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Bioconjugation: Links biomolecules using both amine and click handles.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Supports dual-functional PEGylated conjugates.
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Synthetic Chemistry: Serves as an intermediate for advanced linker design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid hydrolysis of NHS ester.
This product combines dual azide click functionality with amine-reactive NHS chemistry, making it an especially versatile tool for multifunctional conjugation and drug delivery systems.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
