N-Boc-N-bis(PEG2-propargyl)
This product is a multifunctional PEG linker with a Boc-protected amine core and two terminal propargyl (alkyne) groups. The PEG2 arms enhance solubility and accessibility, while the Boc group provides orthogonal protection, making it highly useful for click chemistry, bioconjugation, and probe development.
Key Features and Benefits:
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Dual Propargyl Groups: Support CuAAC or SPAAC click chemistry with azides.
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Boc Protection: Provides acid-labile orthogonal control for stepwise synthesis.
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PEG2 Spacers: Improve solubility and steric flexibility.
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Multifunctional Design: Enables orthogonal and sequential conjugation strategies.
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High Purity: Ensures reproducibility in advanced workflows.
Applications:
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Bioconjugation: Links biomolecules using click and amide chemistry.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Provides PEGylated scaffolds with orthogonal handles.
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Synthetic Chemistry: Useful as a protected intermediate in linker design.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid premature Boc cleavage.
This product integrates orthogonal Boc protection with dual alkyne reactivity, specifically offering solubility and flexibility for multifunctional conjugation and synthetic chemistry.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
