N-(Azido-PEG3)-N-Fluorescein-PEG3-acid
This product is a multifunctional PEG linker containing an azide group, a fluorescein dye, and a terminal carboxylic acid connected by PEG3 spacers. It specifically enables copper-catalyzed or strain-promoted click chemistry, fluorescence imaging, and amide coupling in one compact scaffold.
Key Features and Benefits
-
Azide Group: Reacts with alkynes via CuAAC or SPAAC click chemistry.
-
Fluorescein Dye: Provides bright green fluorescence for imaging and detection.
-
Carboxylic Acid: Couples efficiently with amines to form stable amide bonds.
-
PEG3 Spacers: Improve solubility and reduce steric hindrance.
-
High Purity: Ensures reproducibility in fluorescence and bioconjugation workflows.
Applications
-
Fluorescence Imaging: Labels biomolecules for microscopy, flow cytometry, and diagnostics.
-
Bioconjugation: Links azide- and amine-modified biomolecules.
-
Probe Development: Builds multifunctional fluorescent probes with orthogonal reactivity.
-
Material Science: Functionalizes polymers and nanoparticles with fluorescence and click handles.
Storage and Handling
-
Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
-
Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to light.
This product integrates click reactivity, fluorescent detection, and amide coupling in a PEG3 scaffold, specifically providing a powerful tool for multifunctional labeling and probe development.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
