N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
This product is a multifunctional linker combining an azide group for click chemistry, a fluorescein dye for fluorescence detection, and a terminal carboxylic acid for conjugation. The PEG2 and PEG3 spacers enhance solubility and flexibility, making it especially ideal for bioorthogonal labeling and probe development.
Key Features and Benefits:
-
Azide Group: Enables CuAAC and SPAAC click chemistry with alkynes.
-
Fluorescein Moiety: Provides strong fluorescence for imaging and detection.
-
Carboxylic Acid: Couples efficiently with amines to form amide bonds.
-
PEG Spacers: Improve solubility, reduce steric hindrance, and extend reach.
-
High Purity: Ensures reliable results in imaging and bioconjugation workflows.
Applications:
-
Bioorthogonal Labeling: Facilitates fluorescent tagging via click chemistry.
-
Bioconjugation: Links fluorescent dyes to biomolecules with dual reactivity.
-
Probe Development: Builds multifunctional imaging or diagnostic probes.
-
Drug Delivery: Useful for monitoring conjugate uptake and distribution.
Storage and Handling:
-
Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
-
Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid prolonged light exposure to preserve fluorescein activity.
This product integrates fluorescence detection with click chemistry and carboxyl conjugation, making it an especially versatile reagent for imaging, bioconjugation, and diagnostic research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
