Methylcyclopropene-PEG1-NHS Carbonate (CAS: 1454558-59-8): Overview and Applications
Product Summary
Methylcyclopropene-PEG1-NHS carbonate is a versatile linker used in bioconjugation and drug delivery. It features a cyclopropene group for bioorthogonal reactions, a PEG1 spacer to improve solubility, and an NHS carbonate ester that reacts with primary amines. This setup allows stable attachment to proteins, peptides, and other amine-containing molecules, making it ideal for targeted therapies and diagnostic agents.
Applications
- Targeted Drug Delivery
- Enables specific drug attachment to targeting molecules, enhancing delivery precision.
- Protein and Peptide Conjugation
- Allows stable covalent bonding with proteins and peptides, useful for therapeutic and research applications.
- Biomolecule Labeling
- Facilitates selective labeling of amine-containing biomolecules, aiding in detection and tracking.
- Diagnostic Agent Development
- Useful in creating diagnostic probes, improving sensitivity and specificity in imaging and assays.
- Bioorthogonal Conjugation
- The cyclopropene group supports selective bioorthogonal reactions with tetrazine-containing compounds.
- Functionalized Biomaterials
- Ideal for modifying surfaces and materials, enhancing biosensors and other bioactive interfaces.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
