Mal-amido-PEG4-Val-Cit-PAB-PNP CAS:2003260-12-4 is a small molecule drug that is composed of several functional groups. The Mal-amido group is a type of functional group that is commonly used in bioconjugation reactions, such as protein labeling and drug delivery. The PEG4 group is a polyethylene glycol spacer that is used to improve the solubility and stability of the drug in solution. The Val-Cit group is a dipeptide that contains the amino acids valine and citrulline, and it has been shown to have antitumor activity. The PAB group is a para-aminobenzoic acid that can be used as a linker for drug conjugation. The PNP group is a type of leaving group that is commonly used in organic synthesis.
The combination of these functional groups in Mal-amido-PEG4-Val-Cit-PAB-PNP is designed to create a drug that can be used to target specific biological processes in the body, particularly in the treatment of cancer. The Val-Cit group, for example, has been shown to have potent antitumor activity by inhibiting the activity of proteasomes, which are enzymes that are essential for the survival of cancer cells. The PEG4 spacer and PAB linker can help to improve the solubility and stability of the drug in solution, while the PNP leaving group can be used to activate the drug and facilitate its conjugation to other molecules.
Mal-amido-PEG4-Val-Cit-PAB-PNP represents an important advance in the development of new drugs for the treatment of cancer and other diseases. By targeting specific biological processes in the body and using a combination of functional groups to improve the stability and solubility of the drug in solution, this compound has shown significant promise in improving outcomes for patients and extending their lives.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
