Mal-amido-PEG2 NHS ester
This product is a heterobifunctional linker featuring a maleimide group for selective thiol conjugation and an NHS ester for rapid amine coupling. The PEG2 spacer improves solubility and compact flexibility, making it especially useful in bioconjugation, probe development, and drug delivery.
Key Features and Benefits:
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Maleimide Group: Reacts selectively with thiols to form stable thioether bonds.
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NHS Ester: Couples efficiently with primary amines under mild conditions.
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PEG2 Spacer: Enhances solubility while minimizing steric hindrance.
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Dual Reactivity: Supports thiol- and amine-targeted conjugation.
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High Purity: Ensures reliable, reproducible results in advanced workflows.
Applications:
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Bioconjugation: Links thiol- and amine-containing biomolecules.
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Probe Development: Builds multifunctional probes for diagnostics and imaging.
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Drug Delivery: Provides dual-reactive scaffolds for targeted therapeutics.
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Material Science: Functionalizes polymers, nanoparticles, and biomaterials.
Storage and Handling:
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Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO); avoid hydrolysis of NHS ester.
This product integrates thiol- and amine-reactive groups in a PEG2 scaffold, specifically offering solubility and versatility for multifunctional conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
