m-PEG8-amine
m-PEG8-amine is a high-purity monofunctional PEG linker featuring a terminal primary amine group for efficient conjugation with activated esters, aldehydes, and other electrophiles. The PEG8 spacer specifically enhances solubility in aqueous and organic solvents, improves molecular flexibility, and reduces steric hindrance in bioconjugation and surface modification processes.
Key Features
-
Primary amine group for versatile coupling reactions
-
PEG8 spacer improves hydrophilicity and flexibility
-
High chemical stability and purity
-
Compatible with aqueous and organic systems
Applications
-
Protein, peptide, and small molecule modification
-
Nanoparticle and surface functionalization
-
Antibody–drug conjugates (ADCs)
-
Crosslinking in biomaterials and drug delivery systems
Storage and Handling
-
Store at –20 °C, protected from light and moisture
-
Allow to reach room temperature before opening
-
Avoid repeated freeze–thaw cycles
This product contains a primary amine group for electrophile coupling and a PEG8 spacer specifically for improved solubility, flexibility, and reduced steric hindrance.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.