m-PEG5-t-buyl ester CAS:874208-93-2 is a specialized compound featuring a monomethoxy polyethylene glycol (mPEG) chain with a tert-butyl ester functional group at one end. This unique structure imparts hydrophilic and biocompatible properties, making it an essential reagent in pharmaceutical research and development.
In drug development, m-PEG5-t-buyl ester is widely utilized for PEGylation, a process where the PEG moiety is covalently attached to therapeutic molecules, such as peptides, proteins, or small molecules. PEGylation significantly enhances the pharmacokinetic properties of these therapeutics, improving their solubility, stability, and bioavailability. Moreover, the incorporation of the tert-butyl ester group offers an additional level of protection for sensitive functional groups during synthesis.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
