m-PEG48-NH-Mal is a highly versatile reagent used in chemical and biological research. It contains a 48-unit polyethylene glycol (PEG) chain, a maleimide (Mal) group, and an amine (NH) group. As a result, it is ideal for conjugation reactions, including bioconjugation, protein labeling, and targeted drug delivery. Moreover, the long PEG spacer improves solubility and flexibility, making it suitable for a variety of applications.
m-PEG48-NH-Mal Key Features:
- Maleimide Group: The maleimide group reacts specifically with thiol groups, enabling efficient conjugation with peptides, proteins, and other thiol-containing molecules. Therefore, it provides excellent selectivity in conjugation reactions.
- Amine Group: The amine group allows easy coupling with carboxylate groups. This feature enhances versatility in bioconjugation and drug delivery systems.
- PEG48 Spacer: The long PEG48 chain improves solubility, flexibility, and biocompatibility. Thus, it ensures better performance of conjugates in aqueous environments.
- Water Soluble: It dissolves easily in water and polar solvents. Consequently, it offers flexibility for various formulations and reactions.
- High Purity: This compound ensures consistent and reliable results. As a result, it is perfect for both research and industrial applications.
m-PEG48-NH-Mal Applications:
- Bioconjugation: m-PEG48-NH-Mal efficiently links peptides, proteins, and biomolecules with thiol groups. This makes it ideal for creating stable conjugates for therapeutic and diagnostic purposes.
- Protein Labeling: It can be used for selective labeling of proteins with fluorescent tags, functional groups, or other molecules. Therefore, it is useful for detection and imaging.
- Drug Delivery: The compound plays a crucial role in developing PEGylated drugs. As a result, it enhances solubility, stability, and bioavailability of therapeutic agents.
- Nanotechnology: m-PEG48-NH-Mal functionalizes nanoparticles for targeted drug delivery, imaging, and diagnostic applications. Hence, it is essential in nanomedicine.
- Surface Modification: It modifies the surfaces of biomaterials, nanoparticles, and microarrays. Therefore, it is useful for biosensor development and diagnostic applications.
Conclusion:
In conclusion, m-PEG48-NH-Mal is a powerful tool for chemical and biological research. Its combination of a maleimide group, amine group, and PEG chain allows for efficient conjugation, protein labeling, and drug delivery. Additionally, its high solubility and flexibility make it perfect for various scientific and industrial applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
