m-PEG4-bromide
m-PEG4-bromide is a monofunctional PEG linker containing a methoxy end group, a PEG4 spacer, and a terminal bromide. It enables nucleophilic substitution and functional group installation, offering solubility, medium flexibility, and versatile reactivity.
Key Features and Benefits
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Bromide Group: Acts as a leaving group for nucleophilic substitution reactions.
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Methoxy End Group: Provides stability and hydrophilic character.
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PEG4 Spacer: Enhances solubility with moderate chain length.
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Versatile Reactivity: Enables synthesis of custom PEG derivatives and intermediates.
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High Purity: Ensures reproducibility in chemical and biological workflows.
Applications
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Bioconjugation: Serves as an intermediate for PEGylation strategies.
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Probe Development: Builds functional probes with custom modifications.
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Drug Delivery: Provides PEG scaffolds with reactive handles.
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Organic Synthesis: Useful for generating tailored PEG-based linkers.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates methoxy stability with bromide reactivity in a PEG4 scaffold, specifically offering solubility and versatility for chemical modification.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
