m-PEG4-Bromide CAS:110429-45-3 is a monofunctional PEGylation reagent, composed of a methoxy group and a bromide moiety connected by a 4-unit PEG linker. Its straightforward design facilitates selective bioconjugation, streamlining pharmaceutical research and development processes.The terminal methoxy group ensures the PEG chain remains unreactive, preserving the linker’s properties.The 4-unit PEG linker enhances solubility, biocompatibility, and pharmacokinetics of the resulting bioconjugates.This halide can be transformed into an electrophilic group for conjugation with nucleophilic biomolecules or replaced with other functional moieties.
m-PEG4-Bromide serves as a versatile building block for designing tailored PEGylation reagents. By converting the bromide group to reactive electrophiles, researchers can generate PEGylation agents for conjugating drugs, biomolecules, or imaging probes. The PEG linker improves pharmacokinetic properties and reduces immunogenicity, enabling the development of more effective therapeutics and diagnostics.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
