m-PEG1-NHS ester
This product is a monofunctional PEG linker containing a methoxy end group, a PEG1 spacer, and an NHS ester. It specifically enables efficient amine coupling, offering solubility, compact structure, and high reactivity for synthesis and bioconjugation.
Key Features and Benefits
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NHS Ester: Couples efficiently with primary amines to form stable amide bonds.
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Methoxy Group: Provides stability and hydrophilic character.
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PEG1 Spacer: Ensures compact length with minimal steric hindrance.
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High Reactivity: Enables rapid and efficient conjugation.
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High Purity: Ensures reproducibility in sensitive workflows.
Applications
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Bioconjugation: Labels proteins, peptides, and biomolecules via amide coupling.
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Probe Development: Builds compact probes for diagnostics and imaging.
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Drug Delivery: Provides PEG scaffolds with stable amide-linked modifications.
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Organic Synthesis: Serves as a versatile intermediate in linker chemistry.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates a methoxy group with NHS ester chemistry in a PEG1 scaffold, specifically offering compact, efficient amine conjugation.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
