m-PEG-Succinic Acid, MW 2K
This product is a high-purity, monofunctional PEG derivative with a terminal carboxylic acid introduced via a succinic acid linker. The PEG backbone provides excellent aqueous solubility, flexibility, and biocompatibility, while the terminal acid enables efficient coupling to amines through carbodiimide or other activation chemistries. This reagent is especially ideal for surface modification, drug delivery, and bioconjugation applications.
Key Features and Benefits
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Terminal Carboxylic Acid – Couples readily with primary amines for stable amide bond formation.
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PEG Backbone (MW 2K) – Enhances water solubility, reduces protein adsorption, and increases molecular flexibility.
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Biocompatible – Low immunogenicity and toxicity for biomedical use.
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High Purity – Supplied at >95% purity for reproducible performance.
Applications
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Protein and peptide conjugation
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Antibody–drug conjugate (ADC) linker design
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Nanoparticle and surface functionalization
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Hydrogel and biomaterial synthesis
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Drug delivery system development
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light
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Handling: Dissolve in aqueous buffers or organic solvents as needed; avoid prolonged exposure to moisture before use
This product features a PEG backbone for solubility and biocompatibility, with a terminal carboxylic acid for amine coupling, making it especially suitable for a wide range of bioconjugation and material science applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.