Indocyanine green

Indocyanine green (ICG) CAS:3599-32-4 is a water-soluble tricarbocyanine dye that is commonly used in the field of pharmaceutical research and development. This compound is characterized by a sulfonate group (-SO3-) and a carboxyl group (-COOH) on its chromophore, making it highly water-soluble and capable of undergoing ionization in physiological pH conditions.

Indocyanine green (ICG) CAS:3599-32-4 is widely used as a diagnostic tool, particularly in the field of ophthalmology, where it is used to visualize blood flow in the retina and choroid. The compound is injected intravenously, and its fluorescence properties allow for real-time imaging of blood vessels and microcirculation. ICG has also found application in the field of cardiac imaging, where it is used to assess cardiac output and blood flow.

In addition to its diagnostic properties, ICG has been investigated for its therapeutic potential. Due to its high water solubility and low toxicity, ICG has been explored as a potential photosensitizer in photodynamic therapy, a treatment that utilizes light and a photosensitizer to selectively destroy cancer cells. In preclinical studies, ICG has shown promising results as a photosensitizer, with the potential to be used in the treatment of various cancers.

ICG is also being explored as a drug delivery system, with the ability to encapsulate therapeutic agents and target specific tissues or cells. By conjugating drugs to ICG, it is possible to deliver them directly to the site of action and monitor their distribution in real-time, providing valuable information for drug development and optimization.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.