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Idasanutlin

Catalog #: AP14276
Name: Idasanutlin
Chemical Formula: C31H29Cl2F2N3O4
Molecular Weight: 616.50
CAS: 1229705-06-9
Purity: ≥95%
Availability: In Stock

Idasanutlin

$150.00 – $650.00

UnitPriceQuantity
10 mg$150
25 mg$320
50 mg$450
100mg$650

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SKU: AP14276 Category:
Description

Idasanutlin (RG-7388) is a potent p53-MDM2 inhibitor with IC50 of 6 nM, showing improved in vitro binding and cellular potency/selectivity. IC50 = 30 nM in cancer cell proliferation assay. Induces p53 stabilization, cell cycle arrest and apoptosis in cancer cells expressing wild-type p53. Shows inhibition of tumor growth in the SJSA1 tumor xenograft model. Also inhibits MDR-1 at high concentrations.

AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.

Synonyms
  • Idasanutlin
  • 1229705-06-9
  • 4-((2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid
  • 4-[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)pyrrolidine-2-carbonyl]amino]-3-methoxybenzoic acid
  • 4-((2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-neopentylpyrrolidine-2-carboxamido)-3-methoxybenzoic acid.
  • Benzoic acid, 4-((((2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl)carbonyl)amino)-3-methoxy-
  • Benzoic acid, 4-[[[(2R,3S,4R,5S)-3-(3-chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxy-
  • 5-[9-Isopropyl-8-methyl-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine
  • 4-[[[(2R,3S,4R,5S)-3-(3-Chloro-2-fluorophenyl)-4-(4-chloro-2-fluorophenyl)-4-cyano-5-(2,2-dimethylpropyl)-2-pyrrolidinyl]carbonyl]amino]-3-methoxybenzoic acid
  • 4-{[(2R,3S,4R,5S)-3-(3-chloro-2-fluoro-phenyl)-4-(4-chloro-2-fluoro-phenyl)-4-cyano-5-(2,2-dimethyl-propyl)-pyrrolidine-2-carbonyl]-amino}-3-methoxy-benzoic acid
Shipping & Delivery
Ships within: 24 hours
Storage condition: -20 ° C
Shipping: Ambient Temperature

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581.50≥95% Pricing

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