I-bu-rG Phosphoramidite (CAS 147201-04-5), also known as 5′-O-DMT-2′-O-TBDMS-N2-Isobutyryl-Guanosine-CE Phosphoramidite, is a TBDMS-protected nucleoside phosphoramidite used in RNA oligonucleotide synthesis. This compound, featuring an isobutyryl-protected guanosine, enables precise incorporation of guanosine into RNA sequences during solid-phase synthesis. The TBDMS group protects the 2′-hydroxyl, and the isobutyryl group shields the exocyclic amine of guanosine, allowing for controlled assembly of special oligonucleotides.
Key Features:
- CAS Number: 147201-04-5
- Chemical Structure: 5′-O-DMT-2′-O-TBDMS-N2-Isobutyryl-Guanosine-CE Phosphoramidite
- Protection Groups: TBDMS and isobutyryl protect functional groups during synthesis
- Function: Building block for specialized RNA oligonucleotide synthesis
- Applications: Used in solid-phase RNA synthesis for creating specialized oligonucleotides in research, diagnostics, and therapeutic development
I-bu-rG Phosphoramidite ensures precise, controlled RNA oligonucleotide assembly, making it ideal for advanced genetic research and therapeutic applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
