Hydroxy-PEG8-acid sodium salt CAS:2468714-92-1 is an innovative, water-soluble polyethylene glycol (PEG) derivative designed to facilitate groundbreaking advancements in pharmaceutical research and development. This versatile compound is characterized by a hydroxyl (OH) group at one end, which is highly reactive and can undergo numerous chemical reactions, such as esterification and etherification. At the opposite end, a carboxylic acid (COOH) group is present as a sodium salt, ensuring excellent water solubility and enabling amide coupling reactions with amines.
The PEG8 linker, an octaethylene glycol, serves as a biocompatible and flexible spacer between the two functional groups. This linker imparts valuable properties to the derivative, including enhanced solubility, reduced immunogenicity, and improved pharmacokinetic profiles.
Hydroxy-PEG8-acid sodium salt is widely employed in pharmaceutical research and development due to its various applications in bioconjugation, drug delivery, and prodrug synthesis. The unique combination of functional groups allows for the creation of targeted drug conjugates, resulting in more efficacious therapies with minimal side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
