Hydroxy-PEG4-nitrile is a PEG derivative which contains a hydroxyl group and a nitrile group. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The nitrile group can undergo hydrolysis to form acid and amide. If reduced, it can form a primary amine group. The hydrophilic PEG spacer can increase the solubility in aqueous media.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.