Hydroxy-PEG4-methyl ester
This product is a heterobifunctional PEG derivative with a terminal hydroxyl group and a methyl ester functionality. The PEG4 spacer enhances solubility, hydrophilicity, and flexibility, making it especially useful for bioconjugation, intermediate synthesis, and multifunctional linker design.
Key Features and Benefits:
-
Hydroxyl Group: Provides a versatile handle for further activation or modification.
-
Methyl Ester: Functions as a stable protected acid derivative.
-
PEG4 Spacer: Improves solubility and steric accessibility.
-
Orthogonal Reactivity: Supports stepwise synthesis and conjugation.
-
High Purity: Ensures consistent and reproducible performance.
Applications:
-
Bioconjugation: Enables incorporation into PEGylated scaffolds and conjugates.
-
Drug Delivery: Provides flexible PEG-based linkers for drug carrier systems.
-
Probe Development: Useful in designing PEGylated probes and intermediates.
-
Synthetic Chemistry: Serves as a precursor for carboxyl-functionalized PEG linkers.
Storage and Handling:
-
Storage: Store at –20 °C in a sealed, moisture- and light-protected container.
-
Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain ester stability.
This product combines hydroxyl functionality with a protected methyl ester, specifically offering solubility, flexibility, and synthetic versatility for advanced chemical and bioconjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
