Hydroxy-PEG4-acid sodium salt CAS:2468714-92-1 is a water-soluble, biocompatible polyethylene glycol (PEG) derivative that boasts a unique combination of functional groups, making it a valuable tool in pharmaceutical research and development. This compound features a hydroxyl (OH) group at one end, which is highly reactive and can participate in various chemical reactions, such as esterification and etherification. At the other end, it has a carboxylic acid (COOH) group, which is present as a sodium salt, offering excellent water solubility and the ability to undergo amide coupling reactions with amines.
The PEG4 linker, a tetraethylene glycol, serves as a flexible, biocompatible spacer between the two functional groups. This linker imparts beneficial properties to the derivative, such as reduced immunogenicity, enhanced solubility, and improved pharmacokinetic profiles.
Hydroxy-PEG4-acid sodium salt finds widespread use in pharmaceutical research and development, with applications in bioconjugation, drug delivery, and the synthesis of prodrugs. Its versatile functional groups facilitate the creation of targeted drug conjugates, leading to more effective therapies with reduced side effects.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
