Gly-PEG3-amine (CAS: 2110448-97-8)
Gly-PEG3-amine is a cleavable PEG linker with a glycine residue and a reactive terminal amine group. It supports bioconjugation by forming stable amide bonds with carboxylic acids, activated NHS esters, and other carbonyl-containing compounds. Its PEG3 spacer improves water solubility and reduces steric hindrance, making it ideal for various biomedical applications.
Key Features:
- Functional Groups: Glycine residue and terminal amine for versatile conjugation
- PEG3 Spacer: Enhances solubility and reduces steric interference
Gly-PEG3-amine Applications:
- Bioconjugation: Forms amide bonds for attaching biomolecules
- Antibody-Drug Conjugates (ADCs): Acts as a linker for targeted drug delivery
- Surface Modification: Improves nanoparticle and material biocompatibility
Handling and Storage:
- Molecular Formula: C₁₂H₂₇N₃O₄
- Molecular Weight: 277.36 g/mol
- Purity: ≥95%
- Storage: Store at -20°C, protected from light and moisture
Gly-PEG-amine is widely used in research for bioconjugation, drug delivery, and surface functionalization due to its reactive amine group and solubility-enhancing PEG spacer.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.