Name: Glembatumumab
SKU: AP15510
Availability: InStock

Glembatumumab

$307.00 – $1,095.00

Glembatumumab (CAS 1020264-78-1) is a human IgG2 monoclonal antibody that targets GPNMB, a protein overexpressed in cancers like melanoma and breast cancer. Researchers use it in cancer therapy and antibody-drug conjugates (ADCs) for targeted drug delivery.

Unit

Price

Quantity

1 mg

$307

5 mg

$681

10 mg

$1095

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Glembatumumab (CAS 1020264-78-1) is a fully human IgG2 monoclonal antibody that targets glycoprotein non-metastatic B (GPNMB), a protein overexpressed in various cancers, including melanoma and breast cancer.

Key Features:

Target Specificity: Binds to GPNMB on cancer cells.
Mechanism of Action: Inhibits GPNMB signaling, potentially reducing tumor growth and metastasis.
Molecular Characteristics: Human IgG2 monoclonal antibody.

Applications:

Cancer Therapy: Investigated for treating GPNMB-expressing tumors, including melanoma and breast cancer.
Antibody-Drug Conjugates (ADCs): Used in ADCs, like glembatumumab vedotin, for targeted drug delivery.

Glembatumumab is primarily used in research to assess its potential in targeting GPNMB-expressing cancer cells. Clinical trials are underway to explore its therapeutic benefits in oncology.

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