Folate-PEG3-Acid
High-Purity PEGylated Folic Acid for Targeted Drug Delivery & Bioconjugation
Product Overview
Folate-PEG3-Acid is a PEGylated folic acid derivative featuring a PEG3 spacer and a terminal carboxylic acid functional group. This molecule is widely used as a folate receptor–targeting ligand in drug delivery systems, bioconjugation, and diagnostic probe development.
The PEG3 linker enhances aqueous solubility and provides optimal spatial flexibility, while the carboxyl terminus enables efficient coupling to amines, peptides, polymers, or nanoparticles.
Key Features
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Folate receptor–targeting ligand for cancer and cell-specific delivery
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PEG3 spacer improves solubility and reduces steric hindrance
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Terminal –COOH group for amide bond formation
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Suitable for small-molecule drugs, peptides, proteins, and nanoparticles
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High purity, batch-to-batch consistency
Applications
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Targeted drug delivery (folate receptor–overexpressing cells)
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Antibody-drug conjugates (ADCs) and peptide conjugates
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Nanoparticle and liposome surface functionalization
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Imaging probes and diagnostic reagents
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PROTAC and linker-based conjugation strategies
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
