Fmoc-PEG6-alcohol is a high-purity polyethylene glycol (PEG) linker with an Fmoc protecting group and a hydroxyl (-OH) functional group. It is widely used in peptide synthesis, surface modification, and bioconjugation. Moreover, the PEG6 spacer enhances solubility, increases flexibility, and reduces steric hindrance. Therefore, it is an excellent choice for drug delivery, biomaterial engineering, and pharmaceutical research.
Key Features
- Dual Functionality – Contains an Fmoc-protected amine for controlled deprotection and a hydroxyl group for easy modifications. Consequently, it expands usability in various applications.
- Improved Solubility and Stability – The PEG6 spacer significantly boosts hydrophilicity, ensuring better solubility in both water and organic solvents. As a result, it enhances effectiveness in different environments.
- Optimized Spacer Length – Provides a well-defined PEG6 linker that efficiently minimizes steric hindrance. Thus, it facilitates smoother reactions in bioconjugation processes.
- High Purity and Consistency – Manufactured under strict quality controls to guarantee reliable and reproducible results. This ensures consistency in research and development.
- Broad Application Range – Ideally suited for peptide synthesis, surface functionalization, and drug delivery development. Therefore, it is highly valuable in pharmaceutical and biotechnological innovations.
Applications
- Peptide and Protein Synthesis – Enhances synthesis efficiency and improves solubility. As a result, it is highly beneficial for biomolecular engineering.
- Drug Delivery Systems – Functions as a flexible linker in drug conjugation, enhancing pharmacokinetics and improving bioavailability. Consequently, it leads to better therapeutic outcomes.
- Bioconjugation and Surface Modification – Functionalizes surfaces and biomaterials, ensuring precise and targeted applications. Therefore, it is useful in biotechnology and medicine.
- Polymer and Material Science – Supports polymer functionalization and biomaterial engineering. Ultimately, this leads to greater stability and improved performance in various formulations.
Conclusion
In summary, Fmoc-PEG6-alcohol is a highly effective PEG-based linker that plays a crucial role in peptide synthesis, drug delivery, and surface modification. Furthermore, with its dual functionality, improved solubility, and optimized PEG6 spacer, it provides a dependable and efficient solution for pharmaceutical and biotechnology research. Therefore, its remarkable stability and flexibility make it an indispensable tool for advanced biomedical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.