Fmoc-N-methyl-PEG4-NHS Ester
Fmoc-N-methyl-PEG4-NHS ester is a specialized PEG linker used in peptide chemistry and bioconjugation. This compound features a hydrophilic PEG4 spacer, an Fmoc-protected amine, and an NHS ester, enhancing its versatility and application in various research and pharmaceutical contexts.
Key Features
- PEG4 Spacer: Enhances water solubility and flexibility.
- Fmoc Group: Protects amines during synthesis; removable under basic conditions for further reactions.
- NHS Ester: Reacts with primary amines for stable labeling and conjugation.
Applications
- Peptide Synthesis: Facilitates the creation and modification of peptides.
- Bioconjugation: Labels proteins, oligonucleotides, and other amine-containing molecules.
- Drug Development: Enhances solubility and stability of peptide-based drugs.
Advantages
- Improved Solubility: PEG4 spacer increases solubility in aqueous media.
- Stable Conjugation: NHS ester ensures reliable labeling of primary amines.
- Versatile: Fmoc group allows for further conjugation after deprotection.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.