Fmoc-PEG8-NHS ester CAS:1334170-03-4 is a high-quality, bifunctional crosslinking reagent widely utilized in pharmaceutical research and development. This versatile compound features two distinct functional groups: an Fmoc (9-fluorenylmethoxycarbonyl) group at one end and an NHS (N-hydroxysuccinimide) ester at the other.
The Fmoc group imparts stability and solubility during peptide synthesis and can be easily removed under mild conditions, allowing for the site-specific incorporation of various biomolecules. The NHS ester, on the other hand, is highly reactive towards primary amines, facilitating the covalent conjugation of proteins, peptides, and other amine-containing molecules.
Fmoc-PEG8-NHS ester is particularly useful in the development of drug delivery systems, bioconjugation techniques, and targeted therapeutics. The PEG (polyethylene glycol) linker, with its eight ethylene glycol units, enhances the hydrophilicity and biocompatibility of the crosslinked products, while reducing immunogenicity and increasing in vivo stability.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
