E3 ligase Ligand 9 is a ligand for E3 ubiquitin ligase. Ligase is an enzyme that catalyzes the joining of two molecules, simultaneously hydrolyzing the diphosphate bond in ATP or similar triphosphates. The E3 ligase Ligand 9 can be linked to protein ligands through linkers to form PROTAC or SNIPER.
E3 Ligase ligand 9 (also known as Ligand 9 or E3L9) is an adaptor molecule that acts as an intermediary between two proteins in an ubiquitination pathway. It helps to link an E2 Ubiquitin-conjugating enzyme with an E3 Ubiquitin-protein ligase. This allows the ligase to recognize the target protein and transfer a ubiquitin molecule to it, marking it for degradation by the proteasome.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.