DSG is a water-insoluble, non-cleavable homobifunctional N-hydroxysuccinimide ester (NHS-ester) crosslinker commonly used to bind radiolabeled ligands to cell surface receptors. Due to its membrane permeability, it can be used for intracellular crosslinking. NHS esters are the simplest and most commonly used reactive groups for crosslinking and labeling proteins and peptides. NHS esters react with primary amines at the N-terminus of peptides and amines of lysine residues to form stable covalent amide bonds and release the NHS group.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
