DNP-PEG4-DBCO
This product is a heterobifunctional PEG linker containing a dinitrophenyl (DNP) hapten, a PEG4 spacer, and a dibenzocyclooctyne (DBCO) group. It specifically enables immune recognition and copper-free click chemistry, offering solubility, flexibility, and dual reactivity.
Key Features and Benefits
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DNP Hapten: Provides antigenic recognition in immunological assays and labeling.
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DBCO Group: Reacts rapidly with azides via SPAAC copper-free click chemistry.
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PEG4 Spacer: Enhances solubility and minimizes steric hindrance.
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Dual Reactivity: Combines hapten recognition with bioorthogonal click chemistry.
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High Purity: Ensures reproducibility in sensitive biological workflows.
Applications
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Bioconjugation: Links azide-modified biomolecules while introducing an immunogenic DNP tag.
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Probe Development: Builds multifunctional probes for immune detection and imaging.
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Drug Delivery: Provides PEG scaffolds with bioorthogonal and hapten handles.
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Immunology Research: Useful for antibody detection and immune assay development.
Storage and Handling
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Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates a dinitrophenyl hapten with DBCO click chemistry in a PEG4 scaffold, specifically offering dual reactivity for immunology and conjugation workflows.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.