DNP-PEG3-CH2 Acid
This high-purity PEG linker features a dinitrophenyl (DNP) group for hapten-based antibody recognition and a terminal carboxylic acid for amine coupling. The PEG3 spacer specifically enhances solubility, flexibility, and reduces steric hindrance, enabling efficient bioconjugation in aqueous and organic systems.
Key Features and Benefits
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DNP Group – Recognized by anti-DNP antibodies for targeted detection or capture.
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Carboxylic Acid – Couples efficiently with primary amines via carbodiimide or other activation chemistries.
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PEG3 Spacer – Improves solubility, molecular flexibility, and accessibility of reactive groups.
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High Purity – Supplied at >95% purity for consistent, reproducible results.
Applications
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Antibody-based detection and targeting
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Protein and peptide conjugation
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Multifunctional probe and assay development
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Nanoparticle and biomaterial functionalization
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light
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Handling: Use anhydrous solvents such as DMSO or DMF; avoid prolonged moisture exposure to preserve reactivity
This product combines a DNP group for selective antibody recognition with a reactive carboxylic acid, linked by a PEG3 spacer for solubility and flexibility, making it especially ideal for targeted detection, conjugation, and bioassay applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
