DibromoMal-PEG1-Folate CAS:2739789-12-7 is a bifunctional reagent used for the conjugation of folate to other molecules, such as proteins or nanoparticles. The reagent is composed of a dibromo maleimide group, a short polyethylene glycol (PEG) linker, and a folate group.
The dibromo maleimide group is a highly reactive group that can selectively react with thiol groups on biomolecules, while the PEG linker provides a hydrophilic spacer between the maleimide and folate groups. The folate group is a vitamin that is selectively taken up by cells that express folate receptors, making it an ideal targeting ligand for drug delivery applications.
DibromoMal-PEG1-Folate is commonly used to create targeted drug delivery systems, where drugs are conjugated to the folate group and delivered selectively to cells that overexpress folate receptors. The hydrophilic PEG linker improves the solubility and stability of the conjugate in biological fluids.
DibromoMal-PEG1-Folate is a white to off-white powder that is soluble in a range of polar solvents, such as DMSO, DMF, or ethanol. It should be stored at -20°C in a dry and dark place to maintain its stability and quality.
DibromoMal-PEG1-Folate is a versatile and widely used reagent in drug delivery applications. Its ability to selectively target folate receptor-expressing cells and its hydrophilic PEG linker make it a popular choice among researchers for targeted drug delivery and cancer therapy applications. The dibromo maleimide group provides additional reactivity and flexibility in conjugation strategies, making this reagent a useful addition to the toolbox of bioconjugation chemists.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
