Diazo-PEG3-methyltetrazine is a small molecule drug that is composed of several functional groups. The diazo group is a functional group that contains two nitrogen atoms and is commonly used in organic chemistry as a reactive intermediate. The PEG3 spacer is a type of polyethylene glycol that is used to improve the solubility and stability of the drug in solution. The methyltetrazine group is a type of heterocyclic compound that contains four nitrogen atoms in the ring structure and is known to be highly reactive towards biocompatible groups like trans-cyclooctene.
The combination of these functional groups in Diazo-PEG3-methyltetrazine is designed to create a drug that can be used for bioorthogonal chemistry and targeted drug delivery. Bioorthogonal chemistry refers to the use of chemical reactions that occur selectively and rapidly in living systems without interfering with natural biological processes. Diazo-PEG3-methyltetrazine is known to be highly reactive towards trans-cyclooctene groups, which are often used as biocompatible handles for targeting drugs to specific biological targets in the body. The PEG3 spacer helps to improve the solubility and stability of the drug in solution, making it easier to administer to patients.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.