DBCO-STP Ester

DBCO-STP Ester (CAS: 2268816-75-5)

DBCO-STP Ester modifies proteins, antibodies, and other amine-containing biopolymers with ease. It combines the fast, copper-free click chemistry of the DBCO group with the highly soluble 4-Sulfo-2,3,5,6-tetrafluorophenyl (STP) ester, providing excellent stability and efficiency for aqueous bioconjugation.

Key Features:

• STP Ester: Increases water solubility and offers greater stability against hydrolysis than NHS esters, ensuring consistent results.
• DBCO Group: Facilitates quick, copper-free click chemistry with azides, forming strong bonds without the need for toxic catalysts.
• Hydrolysis Resistance: The STP ester’s stability allows for longer reaction times, giving you more control during the process.

Applications:

• Protein and Antibody Labeling: Works efficiently in water, delivering faster and more accurate labeling.
• Bioconjugation: Connects azide-labeled molecules to amine-containing biomolecules in aqueous environments with ease.
• Click Chemistry: Performs rapid, copper-free click reactions, ideal for live-cell and other sensitive applications.
• Drug Delivery: Attaches therapeutic agents to targeting molecules, improving delivery in water-based systems.

Advantages:

• Enhanced Solubility: Ensures smooth, efficient reactions in water-based environments.
• Superior Stability: Provides better control and efficiency due to its hydrolysis resistance.
• Fast Copper-Free Chemistry: Enables safe, effective labeling without the need for copper.

This reagent gives researchers a reliable, efficient tool for bioconjugation and click chemistry in aqueous environments.