DBCO-SS-amine is a cleavable linker used in bioconjugation. It includes a DBCO group for copper-free click chemistry with azides, a primary amine for binding to carboxyl groups, and a disulfide bond for controlled release under reducing conditions.
Key Features:
- DBCO Group: Enables copper-free click reactions with azides.
- Primary Amine: Binds efficiently to carboxyl groups for stable conjugation.
- Disulfide Bond (SS): Allows controlled release under reducing conditions.
Applications:
- Antibody-Drug Conjugates (ADCs): Links drugs to antibodies for targeted therapy.
- Protein and Peptide Conjugation: Attaches proteins or peptides to other molecules.
- Surface Functionalization: Adds functional groups to surfaces for biosensor development.
Store DBCO-SS-amine at -20°C and dissolve in DCM, THF, acetonitrile, DMF, or DMSO for use.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
