DBCO-PEG6-NH-Boc CAS:2828433-65-2 contains two functional groups, an N-terminal Boc-protected amine (-NH-Boc) and a dibenzocyclooctyne (DBCO) moiety, which is a reactive functional group that is commonly used for bioconjugation reactions.
DBCO-PEG6-NH-Boc is a useful tool in the field of pharmaceutical research and development, particularly in the development of novel drug delivery systems. The PEG chain provides several benefits, such as increased solubility, improved pharmacokinetics, and reduced immunogenicity, making it an ideal candidate for drug delivery applications.
The DBCO moiety of DBCO-PEG6-NH-Boc is known for its ability to react with azide functional groups through the copper-free click chemistry reaction. This reaction is highly selective, efficient, and bioorthogonal, meaning it can be performed in living systems without interfering with biological processes. Therefore, DBCO-PEG6-NH-Boc can be used to conjugate various biomolecules, such as peptides, proteins, antibodies, and nucleic acids, to drug delivery vehicles, such as liposomes, micelles, and nanoparticles.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
