DBCO-PEG-SC(DBCO-PEG-NHS), MW 10Kis a versatile compound. It is composed of several functional groups that make it an ideal reagent for various chemical reactions, including amide bond formation and click chemistry.
One of the key functional groups in DBCO-PEG-NHS is the N-hydroxysuccinimide (NHS) ester. This group reacts readily with amino groups on biomolecules, forming stable amide bonds. This feature has made DBCO-PEG-NHS an essential reagent for conjugating various biomolecules, including peptides, proteins, and antibodies. The conjugation of these biomolecules with DBCO-PEG-NHS enhances their pharmacokinetic and pharmacodynamic properties, allowing for improved efficacy and reduced toxicity.
Another significant functional group in DBCO-PEG-NHS is the dibenzocyclooctyne (DBCO) group. This group participates in the copper-free click reaction, which is a highly efficient and selective bioconjugation technique. This feature has made DBCO-PEG-NHS an important tool in bioorthogonal chemistry and imaging studies.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.