β-D-Tetraacetylgalactopyranoside-PEG2-azide
β-D-Tetraacetylgalactopyranoside-PEG2-azide is a high-purity heterobifunctional PEG linker combining a β-D-tetraacetylgalactopyranoside moiety for glycan-based targeting or recognition with an azide group for copper-catalyzed (CuAAC) or strain-promoted (SPAAC) click chemistry. The PEG2 spacer improves aqueous solubility, flexibility, and reduces steric hindrance, specifically enabling efficient conjugation in both aqueous and organic environments. Its design makes it especially suited for glycosylation studies, targeted delivery, and bioorthogonal labeling applications.
Key Features and Benefits
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β-D-Tetraacetylgalactopyranoside Moiety: Facilitates glycan-mediated targeting, recognition, or functionalization.
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Azide Group: Compatible with CuAAC and SPAAC click chemistry for efficient and selective conjugation.
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PEG2 Spacer: Enhances solubility and molecular flexibility while reducing steric interference.
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Heterobifunctional Design: Allows orthogonal and site-specific conjugations for complex assembly strategies.
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High Purity: Supplied at >95% purity for reliable, reproducible results.
Applications
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Glycan-based targeting in drug delivery and imaging.
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Bioorthogonal labeling and molecular probe development.
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Glycoprotein engineering and glycoconjugate synthesis.
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Nanoparticle surface modification with carbohydrate ligands.
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Research in carbohydrate-mediated cell interactions.
Storage and Handling
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Storage: Store at –20 °C, dry, and protected from light.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid moisture to preserve azide reactivity and acetyl protection.
This product combines glycan-targeting functionality with versatile azide click chemistry, linked by a PEG2 spacer for optimal solubility and flexibility, making it especially ideal for glycobiology, drug delivery, and biomaterials research.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
