Cbz-N-amido-PEG3-CH2COOH contains a Cbz protected amine and a carboxylic acid group. The acid can be used to conjugate with amine-bearing biomolecules such as lysine residue on the proteins and amine modified oligonucleotide and biopolymers. The removal of Cbz group by hydrogenation affords a free amino group, which can be conjugated with biomolecules containing carboxylic acid or its activated ester groups. The PEG spacer increase the solubility of the resulting complex in aqueous media.
Axispharm offers 3000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.