Cbz-N-amido-PEG1-t-butyl ester CAS:1295644-51-7 is a high-quality, synthetic reagent used extensively in pharmaceutical research and development. This bifunctional compound consists of two functional groups: a benzyloxycarbonyl (Cbz) group and a tert-butyl ester group, separated by an amide linkage and a short polyethylene glycol (PEG) spacer.
The Cbz group is a well-known protective group for primary amines, allowing for selective deprotection under mild conditions. The t-butyl ester group is a commonly employed ester protecting group, which is easily removed under acidic conditions. These characteristics make Cbz-N-amido-PEG1-t-butyl ester an invaluable tool for constructing complex bioactive molecules, such as peptides and small molecules.
The presence of the PEG spacer enhances solubility, stability, and biocompatibility of the resulting compounds, making them ideal candidates for pharmaceutical applications. This versatile reagent has facilitated the synthesis of innovative therapeutics, targeting a variety of diseases including cancer, neurodegenerative disorders, and infectious diseases.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.