The aminooxy has been used to conjugate with carbonyl bearing (ketone and aldehyde) biomolecules to form oxime for reversible linkage spacer.Oxime ligation is one of the hot topics in the field of bioconjugation of molecules due to its chemoselectivity and hydrolytic stability.
CBZ–aminooxy–PEG8–acid is a type of linker molecule used to attach different molecules to each other. It is a carboxybenzyl (CBZ)-protected aminooxy–polyethylene glycol (PEG) molecule with eight ethylene glycol units and a carboxylic acid end group. It is commonly used in chemical and biological applications such as antibody–drug conjugates, peptide conjugates, and other biomolecule conjugates.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.