Bis-PEG5-PFP ester
This product is a homobifunctional PEG linker containing reactive pentafluorophenyl (PFP) ester groups at both ends of a PEG5 spacer. It specifically enables efficient amine coupling, crosslinking, and bioconjugation with enhanced solubility and spacing.
Key Features and Benefits
-
Dual PFP Esters: Provides two highly reactive ester groups for amine conjugation.
-
PEG5 Spacer: Improves water solubility and offers moderate flexibility.
-
High Efficiency: PFP esters react readily with primary and secondary amines.
-
Versatile Linker: Supports protein crosslinking, drug delivery, and advanced bioconjugation.
-
High Purity: Ensures reproducibility in demanding research workflows.
Applications
-
Bioconjugation: Couples biomolecules through reactive amine groups.
-
Crosslinking: Links proteins, peptides, or polymers with high selectivity.
-
Drug Delivery: Facilitates the creation of multifunctional PEG scaffolds.
-
Diagnostics: Provides stable linkages for probe and assay development.
-
Organic Synthesis: Serves as a versatile intermediate for PEG-based conjugation chemistry.
Storage and Handling
-
Storage: Store at –20 °C in a sealed, light- and moisture-protected container.
-
Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product integrates two PFP esters across a PEG5 scaffold, specifically offering reliable amine conjugation with solubility and versatility for research and pharmaceutical applications.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
