Bis-Mal-PEG19
This product is a homobifunctional PEG linker containing two maleimide groups connected by a PEG19 spacer. It enables selective thiol coupling at both ends, specifically providing a long, flexible, and highly soluble crosslinker for bioconjugation, drug delivery, and material modification.
Key Features and Benefits
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Dual Maleimide Groups: React selectively with thiols to form stable thioether bonds.
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PEG19 Spacer: Offers extended length, solubility, and molecular flexibility.
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Homobifunctional Design: Supports symmetric crosslinking of biomolecules.
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Long-Chain PEG: Reduces steric hindrance and improves aqueous compatibility.
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High Purity: Ensures reproducibility in sensitive conjugation workflows.
Applications
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Bioconjugation: Crosslinks thiol-containing proteins, peptides, or small molecules.
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Probe Development: Builds multifunctional probes for imaging and diagnostics.
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Drug Delivery: Constructs PEGylated scaffolds for stable therapeutic conjugates.
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Material Science: Functionalizes polymers, nanoparticles, and surfaces with PEG.
Storage and Handling
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Storage: Keep at –20 °C in a sealed, light- and moisture-protected container.
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Handling: Use anhydrous solvents such as DMF or DMSO; avoid prolonged exposure to moisture.
This product combines two thiol-reactive maleimide groups with a long PEG19 chain, specifically offering a versatile and soluble crosslinker for advanced bioconjugation and material science.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
