Biotin-PEG8-NHS Ester (CAS: 2143968-03-8) is a versatile compound commonly used in bioconjugation, protein labeling, and drug delivery applications. The compound combines a biotin group, an 8-unit PEG spacer, and an NHS ester functionality, allowing efficient conjugation with amine-containing molecules. Researchers often rely on it for molecular biology, diagnostics, and therapeutic research.
Key Features:
- Biotin Group: The biotin group ensures strong and specific binding to avidin or streptavidin, making it effective for targeted detection in biochemical assays.
- PEG8 Spacer: The 8-unit PEG spacer improves solubility and biocompatibility, boosting the compound’s performance in both biological and aqueous environments.
- NHS Ester Group: The NHS ester reacts selectively with amine groups, enabling easy conjugation of proteins, peptides, and nucleic acids.
- High Purity: Biotin-PEG8-NHS Ester maintains high purity, providing consistent and reliable results for research and industrial use.
- Water Soluble: It dissolves readily in water and polar solvents, offering flexibility in experimental setups.
Applications:
- Bioconjugation: Researchers use Biotin-PEG8-NHS Ester to link peptides, proteins, and nucleic acids to other molecules, driving drug discovery and diagnostics.
- Protein Labeling: The compound facilitates biotinylation of proteins, making detection and tracking through avidin/streptavidin binding straightforward.
- Drug Delivery: It plays a critical role in targeted drug delivery systems, enhancing the specificity and effectiveness of therapeutic agents.
- Molecular Biology: Commonly used in biotinylation-based assays, such as enzyme-linked immunosorbent assays (ELISAs) and Western blots.
- Diagnostic Tools: The compound also functions in biosensors and other diagnostic applications by enabling the attachment of biomolecules for detection.
Conclusion:
In conclusion, Biotin-PEG8-NHS Ester (CAS: 2143968-03-8) is an essential tool for bioconjugation, protein labeling, and targeted drug delivery. The biotin group, PEG8 spacer, and NHS ester functionality make it ideal for a wide range of molecular biology, diagnostics, and therapeutic applications. With its high purity and excellent solubility, it supports both research and industrial needs.
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