Biotin-PEG6-acid
This product is a heterobifunctional PEG6 linker combining a biotin moiety with a terminal carboxylic acid. The PEG6 spacer provides hydrophilicity and flexibility, while the biotin ensures high-affinity binding to avidin/streptavidin systems, making this reagent especially valuable for targeted bioconjugation and labeling applications.
Key Features and Benefits:
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Biotin Group: Strong, specific binding to avidin and streptavidin proteins.
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Carboxylic Acid Group: Couples efficiently with primary amines for amide bond formation.
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PEG6 Spacer: Provides solubility, flexibility, and reduced steric hindrance.
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High Purity: Ensures reliable performance in sensitive bioconjugation workflows.
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Dual Reactivity: Combines biotin targeting with versatile carboxyl conjugation.
Applications:
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Affinity Labeling: Biotinylation of proteins, peptides, and biomolecules.
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Bioconjugation: Dual-functional linker for targeted labeling and detection.
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Drug Delivery: Enhances solubility and enables biotin-mediated targeting.
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Surface Modification: Functionalizes nanoparticles, polymers, and biosensors.
Storage and Handling:
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Storage: Store at –20 °C, protected from moisture and light.
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Handling: Use anhydrous solvents (e.g., DMF, DMSO) to maintain acid reactivity.
This product provides strong biotin binding with versatile carboxyl reactivity in a flexible PEG spacer, making it an especially powerful tool for bioconjugation and biomolecular labeling.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.
