BCN-PEG2-Val-Ala-PAB CAS:2348405-84-3 is a chemical compound used in bioconjugation and drug delivery. It is composed of several functional groups, including a BCN (trans-cyclooctene) group, a PEG (polyethylene glycol) chain, a Valine-Alanine dipeptide, and a p-aminobenzyloxycarbonyl (PAB) protecting group.
The BCN group in BCN-PEG2-Val-Ala-PAB is highly reactive towards tetrazine-modified molecules, making it an ideal linker for bioorthogonal conjugation reactions. The PEG chain improves the solubility and biocompatibility of the compound, while the dipeptide and PAB groups can be used to target specific cells or tissues.
BCN-PEG2-Val-Ala-PAB is often used to modify the surface of drugs or nanoparticles, enabling targeted delivery to specific cells or tissues. This modification can improve the pharmacokinetics and efficacy of drugs, while also reducing toxicity and immunogenicity. Additionally, it can be used as a starting material for the synthesis of bioconjugates or prodrugs, which are biologically inactive compounds that can be metabolized into active drugs in the body.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.