BCN-PEG12-acid (CAS 2702973-69-9) is a specialized chemical widely used in bioconjugation and drug delivery. It includes a BCN group and a carboxylic acid group, allowing copper-free click chemistry. The compound boasts a polyethylene glycol (PEG) chain with twelve units (PEG12), improving water solubility, bioavailability, and reducing immunogenicity. The extended PEG12 provides maximum flexibility for effective molecule conjugation. The BCN part allows for reactions with azides, advantageous in copper-sensitive biological systems, while the carboxylic acid end provides a site for further conjugation, like creating amide bonds with amines.
AxisPharm offers 5000+ PEG Linkers with high purity. Different kinds of PEG Reagents may be available by custom synthesis.